Samuel Andresen-Anderson is a failing writer and college professor whose mother abandoned him when he was a child, without explanation. She comes back into his life in a most unexpected way, by committing a ridiculous but highly publicized crime. Samuel plans to seize the moment and write a tell-all book to help pay off the advance for a book he has yet to write. It turns out, he knew very little about his mother, her parents, and the forces which have shaped him. Set in the present and the 1960s, Chicago and New York, The Nix explores the mother-son relationship and the secrets that shape families and friendships.